Zesty
> Gigadeath vs walky talkys
Well, you could argue Giga is better because it's shorter, and in NG+ you can dispose of him much more easily. But it's also much more frustrating than walky talkys.
> S rank
Isn't it about efficiency, though? That's what some people would argue, in fact: that DMC being combo based is a misconception. Indeed, it's definitely true for 1, where the style meter doesn't matter at all.
That said, I don't know, it just feels wrong to play DMC without going for ranks (except on your first or second run). Without that, vanilla DMC 3 would lack challenge.
> NG2 NUR
Yes, you can use items. And no, using them doesn't give you a worse rank. In fact, the system is FAR more lenient than DMC3, and it's questionable in its quality, as for instance it doesn't rank you based on how much Ninpo you used, only on how much you have lefr at the end of the level. Though you could argue its flexibility is a pro as well.
So you can use all Ninpo you want, then use an item to restore your Ninpo bar, and then end the level and still get max Karma points. In NGB your essence cap is 99k, so if you start the level with that amount of money, you'll get 0 Karma for currency. Here, you have a 999k cap IIRC but farming essence is much harder.
Btw, there are no damage runs even for NG2, but I don't think they are worth it, nor fun at all. There is also a NUR on YouTube, but it's only for the first 3 chapters.
If you want to try it, you'll better have at least a few vanilla runs under your belt anyway. One advantage, though, is that you won't be spending money upgrading weapons, so you'll have more for healing items.
> MN bad design
And archers (seriously, they are obnoxious on MN), bow sections (the bow is another very questionable mechanic in NG), armored dogs' grab, those earth worms, red dragons being so spongy, and more. The Water Dragon is another highlight, I'd say.
Some other stuff like the Worm in Chapter 9, or shoiting those small flying demons with the bow, isn't even really difficult, just bad/boring.
Overall, NGB on MN is almost a joke compared to this one on MN. The really frustrating moments in Black are few and far between, but here? It's in almost every damn chapter.