Knife Only is possible, I've done it when I was younger. First did it on Normal and then on Pro. There are of-course run-exceptions as there usually are with these types of heavy restriction runs.
You have to use your gun to shoot some crates in 2-1 near the waterfall for example and to shoot the driver of the drill. Lava-room also requires a pistolshot IIRC. Water-room needs a few to stagger some enemies with Ashley. Salazar cannot be knifed, you need to use a weapon. Generally speaking to add some challenge players use an un-upgraded Handgun or Punisher for that fight. You'll need around 500 rounds to get him down.
Saddler is perfectly doable, doubly so if you allow usage of the cranes (I did).
Hardest part of the run was, for me, the Knights room, Waterroom and the bulldozer section. That part was just pure luck on my part, I know people struggle with it immensely but I got insanely lucky there, twice I feel. Note that you can run past a lot of tough fights, and I used some despawn tactics. I'm not above playing dirty haha. Most bosses were pretty easy if you managed to get a good loop.
Agreed, honestly around the time I reach Disc 2 I kind of zone out. The village and castle are the best parts for sure. The Island is good too, but just too many heavy combat sections imo and I don't like its style if you get me. I have the same problem with other games I adore like God Hand and Ninja Gaiden II. Fantastic games but a tad too long for my taste.
> Nioh 2 thread
I'm just happy people are talking!