Fantastic stuff. Shows a big insight into how Mikami works, but also gives further credence to game-designers not understanding what made their games great. Mikami still sees the static-camera as a technical limitation and the over-the-shoulder camera as the 'evolution' of that idea and superior in every aspect. Going as far as being extremely embarresed and asking fans to 'shut up' when they try to convince him otherwise.
Gameplay-wise he seems more to be the guy of the core vision, the idea, so I have a feeling elements like the core-combat of RE4 for example are more his staff that built those around his vision if you get me.
He is showing his age and some familiar concepts are coming back, like his note that you make your best products around the time that you are 30. Since you're still young enough to be energized, but wise enough through experience. As such he still considers RE4 his best game.
One very interesting point though is how in RE4 he was Producer and Director, making it far easier for him to make decisions and how with RE2 he and the crew had a lot of problems, as Mikami and Kamiya had different visions and ideas at times making them unsure on who to listen to. He feels that might be the reason why RE4 was so good as well. He does go on to briefly mention Dead Space as well and its evolution through its three games and how RE changed and never had a 'core', since every title in the series had a different director, making RE4 less of a departure than one would think in his eyes.
Overall, great watch, highly recommended.